Spent many hours on this. Here’s what worked for me.

1. Close VS and IE.
   
2. Run cmd like a boss (as Administrator)
   
3. Type in

   regsvr32 “C:\Program Files (x86)\Common Files\microsoft shared\VS7Debug\pdm.dll”
   regsvr32 “C:\Program Files (x86)\Common Files\microsoft shared\VS7Debug\msdbg2.dll”
   

4. Open regedit and navigate to HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer\Main
   
5. Create a DWORD(32) value named TabProcGrowth. Leave the value as 0.
   
6. Launch VS, script debugging should now work.